Fenbendazole (FZ) is an anthelmintic drug used to treat parasitic worms such as ascarids, whipworms, hookworms, and a single species of tapeworm in humans and animals. It is part of the benzimidazole carbamate family and has cancer-fighting properties.
This medication has come into the spotlight after a man publicly documented his experience using it to cure his stage 4 lung cancer. There is also growing scientific evidence that supports this claim.
What is Fenbendazole?
Fenbendazole (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl) carbamate) is a broad spectrum benzimidazole anthelmintic approved for veterinary use in numerous animal species. It is used against a number of gastrointestinal parasites such as giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms and pinworms, and parasites of the lungs such as Aelurostrongylus and Paragonimiasis.
It has long been known that benzimidazole drugs such as albendazole and mebendazole have anti-cancer effects in laboratory experiments. These effects are caused by disruption of the microtubules and interference with the metabolic process of cancer cells.
In human cells, microtubules help to ensure that chromosomes are separated equally during cell division (mitosis). When this happens, the chromosomes then get delivered to opposite sides of the cell for segregation into two individual cells. During mitosis, if the microtubules are not properly stabilized, the chromosomes may become misaligned and not be distributed evenly. Drugs that interfere with the formation of microtubules can prevent the chromosomes from being evenly distributed.
How is Fenbendazole Used?
Fenbendazole is an anthelmintic drug that eliminates parasitic worms. It’s part of the benzimidazole family, which also includes mebendazole, which is available to treat certain gut infections. But scientific studies show that fenbendazole can also disrupt the microtubules of cancer cells, starving them and inhibiting their growth.
These studies were carried out using a variety of cell lines and tumor models, including human pancreatic cancer. In addition, a 2021 press release by Johns Hopkins Medicine reported that mebendazole and other drugs in the benzimidazole class can block proliferation and promote regression of multiple types of deadly cancer in mice.
While it is impossible to attribute Tippens’s apparent cure solely to fenbendazole, the fact that this deworming medication has been shown to have significant anti-tumor activity supports its use alongside other traditional cancer treatments. Furthermore, fenbendazole is readily available in many countries and is inexpensive to produce. It’s important to work with an integrative healthcare professional when incorporating fenbendazole into your pet’s treatment plan. This ensures the correct dosage and avoids interactions with other medications or supplements that could reduce its effectiveness.
How is Fenbendazole Safe?
Fenbendazole has been shown in multiple scientific journal papers to successfully kill tumors and promote regression in cancer patients with large B-cell lymphoma that had metastasized, as well as bladder cancer and renal cell carcinoma. It is an effective and safe treatment with minimal side effects compared to other medications used in chemotherapy.
The antibiotic has been shown to stabilize WT p53, provide moderate microtubule disruption and interfere with cancer cells’ glucose metabolism, thus starving them. It has also been shown to cause cell cycle arrest in tumors, resulting in the death of cells that would otherwise survive and grow into more tumors.
Despite this, fenbendazole has not been tested in clinical trials in humans for cancer. It is available without a prescription in several countries and is relatively inexpensive to produce. Nevertheless, many people have chosen not to wait for the lengthy bureaucratic process of scientific data to be published and are following the protocol at their own risk, claiming that it works for them.
What are the Side Effects of Fenbendazole?
Fenbendazole is a common medication that can be purchased online without prescription. It is used to treat parasites (roundworms, hookworms, whipworms, and certain tapeworms) in animals under the brand names Panacur or Safe-Guard. It has recently been brought back into the spotlight after videos of a guy who claimed to have cured his small-cell lung cancer using fenbendazole and DCA were posted on Facebook and TikTok.
While research into fenbendazole is limited, the medication appears to be well-tolerated by humans with few side effects. It also has a high safety margin and can be used to treat a wide variety of animal species.
In addition to causing proteasomal interference and microtubule disruption, fenbendazole has shown the ability to impede glucose absorption in cancer cells. This prevents the cells from getting the glucose they need to thrive, starving them of their fuel. In one experiment, the growth of unirradiated tumors was not altered by three fenbendazole treatments given the day before and two hours before irradiation with 10 Gy. fenben for humans